Quality: Then … now … and always

Mcnp Software Quality: Then and Now

MCNP is the Monte Carlo N-Particle radiation transport code whose history dates back more than half a century to the early days of computing. From a simple beginning, its uses have grown to include fields such as criticality safety, radiation shielding, oil well logging, and medical imaging and diagnostics and an international user community of over 3000 users. This large user community could o...

Schizophrenia: Then and Now

EPS—Then and Now

"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was conside...

Then and Now

Fluoroquinolones: then and now.

Fluoroquinolones were discovered in the 1960s as a derivative of the antimalarial drug chloroquine. Over the past 40 years, many fluoroquinolones have been developed for use in human and veterinary medicine. As with all classes of antibiotics, resistance to fluoroquinolones is a serious concern, and multiple avenues for resistance are being investigated. Resistance-associated point mutations in...